Allosteric Regulation of the Discriminative Responsiveness of Retinoic Acid Receptor to Natural and Synthetic Ligands by Retinoid X Receptor and DNA

Transcriptional activation by retinoids is mediated through two families of nuclear receptors, all-trans-retinoic acid (RARs) and 9-cis retinoic acid receptors (RXRs). Conformationally restricted retinoids are used to achieve selective activation of RAR isotype α, β or γ, which reduces side effects...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Mouchon, Arnaud, Delmotte, Marie-Hélène, Formstecher, Pierre, Lefebvre, Philippe
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1999
Assuntos:	Transcriptional Regulation
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84101/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10082574/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.4.3073
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