HOXA9 Forms Triple Complexes with PBX2 and MEIS1 in Myeloid Cells

Aberrant activation of the HOX, MEIS, and PBX homeodomain protein families is associated with leukemias, and retrovirally driven coexpression of HOXA9 and MEIS1 is sufficient to induce myeloid leukemia in mice. Previous studies have demonstrated that HOX-9 and HOX-10 paralog proteins are unique amon...

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Bibliographische Detailangaben
Hauptverfasser: Shen, Wei-Fang, Rozenfeld, Sophia, Kwong, Angela, Kömüves, Laszlo G., Lawrence, H. Jeffrey, Largman, Corey
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 1999
Schlagworte:
Transcriptional Regulation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC84099/
https://ncbi.nlm.nih.gov/pubmed/10082572
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