HOXA9 Forms Triple Complexes with PBX2 and MEIS1 in Myeloid Cells

Aberrant activation of the HOX, MEIS, and PBX homeodomain protein families is associated with leukemias, and retrovirally driven coexpression of HOXA9 and MEIS1 is sufficient to induce myeloid leukemia in mice. Previous studies have demonstrated that HOX-9 and HOX-10 paralog proteins are unique amon...

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Hlavní autoři: Shen, Wei-Fang, Rozenfeld, Sophia, Kwong, Angela, Kömüves, Laszlo G., Lawrence, H. Jeffrey, Largman, Corey
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 1999
Témata:
Transcriptional Regulation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC84099/
https://ncbi.nlm.nih.gov/pubmed/10082572
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