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Polypyrimidine Tract Binding Protein Functions as a Repressor To Regulate Alternative Splicing of α-Actinin Mutally Exclusive Exons

The smooth muscle (SM) and nonmuscle (NM) isoforms of α-actinin are produced by mutually exclusive splicing of an upstream NM exon and a downstream SM-specific exon. A rat α-actinin genomic clone encompassing the mutually exclusive exons was isolated and sequenced. The SM exon was found to utilize t...

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Publicat a:Mol Cell Biol
Autors principals: Southby, Justine, Gooding, Clare, Smith, Christopher W. J.
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1999
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84063/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10082536/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.4.2699
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