Interleukin-2 (IL-2) Regulates the Accessibility of the IL-2-Responsive Enhancer in the IL-2 Receptor α Gene to Transcription Factors

Interleukin-2 (IL-2) responsiveness of T lymphocytes is controlled through transcription of the IL-2 receptor (IL-2R) α subunit by antigen and by IL-2 itself. IL-2 induces IL-2Rα transcription via an IL-2-responsive enhancer (IL-2rE), whose activity depends on the cooperative binding of IL-2-induced...

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Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Rusterholz, Corinne, Henrioud, Patricia Corthésy, Nabholz, Markus
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 1999
Schlagworte:	Transcriptional Regulation
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84061/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10082534/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.4.2681
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