Double-Stranded-RNA-Activated Protein Kinase PKR Enhances Transcriptional Activation by Tumor Suppressor p53

The tumor suppressor p53 plays a key role in inducing G(1) arrest and apoptosis following DNA damage. The double-stranded-RNA-activated protein PKR is a serine/threonine interferon (IFN)-inducible kinase which plays an important role in regulation of gene expression at both transcriptional and trans...

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Auteurs principaux: Cuddihy, Andrew R., Li, Suiyang, Tam, Nancy Wai Ning, Wong, Andrew Hoi-Tao, Taya, Yoichi, Abraham, Ninan, Bell, John C., Koromilas, Antonis E.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 1999
Sujets:
Transcriptional Regulation
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC84040/
https://ncbi.nlm.nih.gov/pubmed/10082513
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