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Double-Stranded-RNA-Activated Protein Kinase PKR Enhances Transcriptional Activation by Tumor Suppressor p53

The tumor suppressor p53 plays a key role in inducing G(1) arrest and apoptosis following DNA damage. The double-stranded-RNA-activated protein PKR is a serine/threonine interferon (IFN)-inducible kinase which plays an important role in regulation of gene expression at both transcriptional and trans...

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Published in:Mol Cell Biol
Main Authors: Cuddihy, Andrew R., Li, Suiyang, Tam, Nancy Wai Ning, Wong, Andrew Hoi-Tao, Taya, Yoichi, Abraham, Ninan, Bell, John C., Koromilas, Antonis E.
Format: Artigo
Language:Inglês
Published: Taylor & Francis 1999
Subjects:
Transcriptional Regulation
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84040/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10082513/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.4.2475
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