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Telomerase Activity Is Sufficient To Allow Transformed Cells To Escape from Crisis

The introduction of simian virus 40 large T antigen (SVLT) into human primary cells enables them to proliferate beyond their normal replicative life span. In most cases, this temporary escape from senescence eventually ends in a second proliferative block known as “crisis,” during which the cells ce...

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Autori principali: Halvorsen, Tanya L., Leibowitz, Gil, Levine, Fred
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC83979/
https://ncbi.nlm.nih.gov/pubmed/10022873
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