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The Gab1 PH Domain Is Required for Localization of Gab1 at Sites of Cell-Cell Contact and Epithelial Morphogenesis Downstream from the Met Receptor Tyrosine Kinase

Stimulation of the hepatocyte growth factor (HGF) receptor tyrosine kinase, Met, induces mitogenesis, motility, invasion, and branching tubulogenesis of epithelial and endothelial cell lines in culture. We have previously shown that Gab1 is the major phosphorylated protein following stimulation of t...

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Auteurs principaux: Maroun, Christiane R., Holgado-Madruga, Marina, Royal, Isabelle, Naujokas, Monica A., Fournier, Tanya M., Wong, Albert J., Park, Morag
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 1999
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC83972/
https://ncbi.nlm.nih.gov/pubmed/10022866
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