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Activation of Transcription by Metabolic Intermediates of the Pyrimidine Biosynthetic Pathway

Saccharomyces cerevisiae responds to pyrimidine starvation by increasing the expression of four URA genes, encoding the enzymes of de novo pyrimidine biosynthesis, three- to eightfold. The increase in gene expression is dependent on a transcriptional activator protein, Ppr1p. Here, we investigate th...

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Detalhes bibliográficos
Main Authors: Flynn, Paul J., Reece, Richard J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC83945/
https://ncbi.nlm.nih.gov/pubmed/9858611
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