Ribosomal Pausing and Scanning Arrest as Mechanisms of Translational Regulation from Cap-Distal Iron-Responsive Elements

Iron regulatory protein 1 (IRP-1) binding to an iron-responsive element (IRE) located close to the cap structure of mRNAs represses translation by precluding the recruitment of the small ribosomal subunit to these mRNAs. This mechanism is position dependent; reporter mRNAs bearing IREs located furth...

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הוצא לאור ב:	Mol Cell Biol
Principais autores:	Paraskeva, Efrosyni, Gray, Nicola K., Schläger, Britta, Wehr, Kristina, Hentze, Matthias W.
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Taylor & Francis 1999
נושאים:	Gene Expression
גישה מקוונת:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC83937/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9858603/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.1.807
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