Siah-1 N-Terminal RING Domain Is Required for Proteolysis Function, and C-Terminal Sequences Regulate Oligomerization and Binding to Target Proteins

The Drosophila seven in absentia (sina) gene was initially discovered because its inactivation leads to R7 photoreceptor defects. Recent data indicate that Sina binds to the Sevenless pathway protein Phyllopod, and together they mediate degradation of Tramtrack, a transcriptional repressor of R7 cel...

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Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Hu, Gang, Fearon, Eric R.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 1999
Schlagworte:	Cell Growth and Development
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC83929/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9858595/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.1.724
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