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Siah-1 N-Terminal RING Domain Is Required for Proteolysis Function, and C-Terminal Sequences Regulate Oligomerization and Binding to Target Proteins

The Drosophila seven in absentia (sina) gene was initially discovered because its inactivation leads to R7 photoreceptor defects. Recent data indicate that Sina binds to the Sevenless pathway protein Phyllopod, and together they mediate degradation of Tramtrack, a transcriptional repressor of R7 cel...

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Publicado en:Mol Cell Biol
Principais autores: Hu, Gang, Fearon, Eric R.
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 1999
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC83929/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9858595/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.1.724
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