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Analysis of Mice with Single and Multiple Copies of Transgenes Reveals a Novel Arrangement for the λ5-V(preB1) Locus Control Region

The murine λ5-V(preB1) locus encodes two proteins that form part of the pre-B-cell receptor and play a key role in B-lymphocyte development. We have identified a locus control region (LCR) which is responsible for coordinate activation of both genes in pre-B cells. Analysis of mice with single and m...

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Autors principals: Sabbattini, Pierangela, Georgiou, Andrew, Sinclair, Calum, Dillon, Niall
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 1999
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC83924/
https://ncbi.nlm.nih.gov/pubmed/9858590
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