Abnormal, Error-Prone Bypass of Photoproducts by Xeroderma Pigmentosum Variant Cell Extracts Results in Extreme Strand Bias for the Kinds of Mutations Induced by UV Light

Xeroderma pigmentosum (XP) is a rare genetic disease characterized by a greatly increased susceptibility to sunlight-induced skin cancer. Cells from the majority of patients are defective in nucleotide excision repair. However, cells from one set of patients, XP variants, exhibit normal repair but a...

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Publié dans:	Mol Cell Biol
Auteurs principaux:	McGregor, W. Glenn, Wei, Dong, Maher, Veronica M., McCormick, J. Justin
Format:	Artigo
Langue:	Inglês
Publié:	Taylor & Francis 1999
Sujets:	DNA Dynamics and Chromosome Structure
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC83873/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9858539/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.1.147
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