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Calmodulin Antagonist W-7 Enhances Intermediate Conductance Ca(2+)- Sensitive Basolateral Potassium Channel (IK(Ca)) Activity in Human Colonic Crypts
Intermediate conductance potassium (IK(Ca)) channels are exquisitively Ca(2+) sensitive, intracellular Ca(2+) regulating channel activity by complexing with calmodulin (CaM), which is bound to the cytosolic carboxyl tail. Although CaM antagonists might be expected to decrease IK(Ca) channel activity...
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| Published in: | J Membr Biol |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Springer US
2021
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8328907/ https://ncbi.nlm.nih.gov/pubmed/34313792 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00232-021-00193-y |
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