TREM-1(+) Macrophages Define a Pathogenic Cell Subset in the Intestine of Crohn’s Disease Patients

BACKGROUND AND AIMS: Uncontrolled activation of intestinal mononuclear phagocytes [MNPs] drives chronic inflammation in inflammatory bowel disease [IBD]. Triggering receptor expressed on myeloid cells 1 [TREM-1] has been implicated in the pathogenesis of IBD. However, the role of TREM-1(+) cell subs...

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Bibliographische Detailangaben
Veröffentlicht in:J Crohns Colitis
Hauptverfasser: Caër, Charles, Gorreja, Frida, Forsskåhl, Sophia K, Brynjolfsson, Siggeir F, Szeponik, Louis, Magnusson, Maria K, Börjesson, Lars G, Block, Mattias, Bexe-Lindskog, Elinor, Wick, Mary Jo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2021
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8328300/
https://ncbi.nlm.nih.gov/pubmed/33537747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ecco-jcc/jjab022
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