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Serum metabolites detect the presence of advanced fibrosis in derivation and validation cohorts of patients with non-alcoholic fatty liver disease

OBJECTIVE: Non-invasive and accurate diagnostic tests for the screening of disease severity in non-alcoholic fatty liver disease (NAFLD) remain a major unmet need. Therefore, we aimed to examine if a combination of serum metabolites can accurately predict the presence of advanced fibrosis. DESIGN: T...

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Bibliographic Details
Published in:Gut
Main Authors: Caussy, Cyrielle, Ajmera, Veeral H, Puri, Puneet, Li-Shin Hsu, Cynthia, Bassirian, Shirin, Mgdsyan, Mania, Singh, Seema, Faulkner, Claire, Valasek, Mark A, Rizo, Emily, Richards, Lisa, Brenner, David A, Sirlin, Claude B, Sanyal, Arun J, Loomba, Rohit
Format: Artigo
Language:Inglês
Published: 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8328048/
https://ncbi.nlm.nih.gov/pubmed/30567742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2018-317584
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