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Novel link between gut-microbiome derived metabolite and shared gene-effects with hepatic steatosis and fibrosis in NAFLD

Previous studies have shown that gut-microbiome is associated with nonalcoholic fatty liver disease (NAFLD). We aimed to examine if serum metabolites especially those derived from the gut-microbiome have a shared gene-effect with hepatic steatosis and fibrosis. This is a cross-sectional analysis of...

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Veröffentlicht in:Hepatology
Hauptverfasser: Caussy, Cyrielle, Hsu, Cynthia, Lo, Min-Tzu, Liu, Amy, Bettencourt, Ricki, Ajmera, Veeral H., Bassirian, Shirin, Hooker, Jonathan, Sy, Ethan, Richards, Lisa, Schork, Nicholas, Schnabl, Bernd, Brenner, David A., Sirlin, Claude B., Chen, Chi-Hua, Loomba, Rohit
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6151296/
https://ncbi.nlm.nih.gov/pubmed/29572891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.29892
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