Intratumoral talimogene laherparepvec injection with concurrent preoperative radiation in patients with locally advanced soft-tissue sarcoma of the trunk and extremities: phase IB/II trial

BACKGROUND: Soft-tissue sarcomas (STS) in the extremities and trunk treated with standard-of-care preoperative external beam radiation therapy (EBRT) followed by surgical resection are associated with local and distant relapses. In preclinical studies, oncolytic virotherapy in sarcoma has demonstrat...

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Bibliografski detalji
Izdano u:J Immunother Cancer
Glavni autori: Monga, Varun, Miller, Benjamin J, Tanas, Munir, Boukhar, Sarag, Allen, Bryan, Anderson, Carryn, Stephens, Laura, Hartwig, Stacey, Varga, Steven, Houtman, Jon, Wang, Lei, Zhang, Weizhou, Jaber, Omar, Thomason, Jon, Kuehn, David, Rajput, Maheen, Metz, Catherine, Zamba, K.D., Mott, Sarah, Abanonu, Chinemerem, Bhatia, Sudershan, Milhem, Mohammed
Format: Artigo
Jezik:Inglês
Izdano: BMJ Publishing Group 2021
Teme:
Oncolytic and Local Immunotherapy
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8327848/
https://ncbi.nlm.nih.gov/pubmed/34330766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2021-003119
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