Identification of TBX15 as an adipose master trans regulator of abdominal obesity genes

BACKGROUND: Obesity predisposes individuals to multiple cardiometabolic disorders, including type 2 diabetes (T2D). As body mass index (BMI) cannot reliably differentiate fat from lean mass, the metabolically detrimental abdominal obesity has been estimated using waist-hip ratio (WHR). Waist-hip rat...

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Detalhes bibliográficos
Publicado no:Genome Med
Main Authors: Pan, David Z., Miao, Zong, Comenho, Caroline, Rajkumar, Sandhya, Koka, Amogha, Lee, Seung Hyuk T., Alvarez, Marcus, Kaminska, Dorota, Ko, Arthur, Sinsheimer, Janet S., Mohlke, Karen L., Mancuso, Nicholas, Muñoz-Hernandez, Linda Liliana, Herrera-Hernandez, Miguel, Tusié-Luna, Maria Teresa, Aguilar-Salinas, Carlos, Pietiläinen, Kirsi H., Pihlajamäki, Jussi, Laakso, Markku, Garske, Kristina M., Pajukanta, Päivi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
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Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8327600/
https://ncbi.nlm.nih.gov/pubmed/34340684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-021-00939-2
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