Regulation of alternative splicing in human obesity loci

OBJECTIVE: Genome-wide association studies (GWAS) have identified multiple obesity susceptibility loci, yet the mechanisms by which these loci influence obesity remain unclear. We hypothesized that alternative splicing could contribute to obesity by regulating the transcriptomic and proteomic divers...

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Detalhes bibliográficos
Publicado no:Obesity (Silver Spring)
Main Authors: Kaminska, Dorota, Käkelä, Pirjo, Nikkola, Elina, Venesmaa, Sari, Ilves, Imre, Herzig, Karl-Heinz, Kolehmainen, Marjukka, Karhunen, Leila, Kuusisto, Johanna, Gylling, Helena, Pajukanta, Päivi, Laakso, Markku, Pihlajamäki, Jussi
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5215786/
https://ncbi.nlm.nih.gov/pubmed/27515906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/oby.21587
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