Berberine Reduces Aβ(42) Deposition and Tau Hyperphosphorylation via Ameliorating Endoplasmic Reticulum Stress

Alzheimer’s disease (AD) is tightly related to endoplasmic reticulum stress (ER stress), which aggravates two dominant pathological manifestations of AD: senile plaques and neurofibrillary tangles. Berberine is widely applied in the clinical treatment of many diseases and is reported to have anti-AD...

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Vydáno v:Front Pharmacol
Hlavní autoři: Wu, Yue, Chen, Qingjie, Wen, Bing, Wu, Ninghua, He, Benhong, Chen, Juan
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8327086/
https://ncbi.nlm.nih.gov/pubmed/34349640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.640758
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