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Berberine Ameliorates Diabetes-Associated Cognitive Decline through Modulation of Aberrant Inflammation Response and Insulin Signaling Pathway in DM Rats

Background: Memory-impairment was one of the common characteristics in patients with diabetes mellitus. The release of chronic inflammation mediators and insulin resistance in diabetic brain gave rise to the generation of toxic factor Aβ42 which was the marker of Alzheimer’s disease. In addition, th...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Front Pharmacol
Hauptverfasser: Chen, Qingjie, Mo, Ran, Wu, Ninghua, Zou, Xin, Shi, Cai, Gong, Jing, Li, Jingbin, Fang, Ke, Wang, Dingkun, Yang, Deshen, Wang, Kaifu, Chen, Juan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5460072/
https://ncbi.nlm.nih.gov/pubmed/28634451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00334
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