Berberine Ameliorates Diabetes-Associated Cognitive Decline through Modulation of Aberrant Inflammation Response and Insulin Signaling Pathway in DM Rats

Background: Memory-impairment was one of the common characteristics in patients with diabetes mellitus. The release of chronic inflammation mediators and insulin resistance in diabetic brain gave rise to the generation of toxic factor Aβ42 which was the marker of Alzheimer’s disease. In addition, th...

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Detalles Bibliográficos
Publicado en:Front Pharmacol
Main Authors: Chen, Qingjie, Mo, Ran, Wu, Ninghua, Zou, Xin, Shi, Cai, Gong, Jing, Li, Jingbin, Fang, Ke, Wang, Dingkun, Yang, Deshen, Wang, Kaifu, Chen, Juan
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2017
Assuntos:
Pharmacology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5460072/
https://ncbi.nlm.nih.gov/pubmed/28634451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00334
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