Resveratrol-induced Sirt1 phosphorylation by LKB1 mediates mitochondrial metabolism

The NAD(+)-dependent deacetylase Sirt1 has been implicated in the prevention of many age-related diseases, including cancer, type 2 diabetes, and cardiovascular disease. Resveratrol, a plant polyphenol, exhibits antiaging, antitumor, and vascular protection effects by activating Sirt1. However, the...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Huang, Yuanyuan, Lu, Jianlin, Zhan, Li, Wang, Ming, Shi, Ronghua, Yuan, Xiao, Gao, Xinjiao, Liu, Xing, Zang, Jianye, Liu, Wei, Yao, Xuebiao
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8326426/
https://ncbi.nlm.nih.gov/pubmed/34216621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100929
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