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Transcriptional regulation of CYP19 by cohesin-mediated chromosome tethering in human granulosa cells
Human CYP19 spans a region of chromosome 15 of approximately 130 kb and encodes aromatase, an enzyme required for estrogen synthesis. In the human granulosa cell-line KGN, there are seven open chromatin regions within the CYP19 locus. In this study, we demonstrate that two of these regions ~40 kb up...
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| 出版年: | Biochem Biophys Rep |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Elsevier
2021
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8326343/ https://ncbi.nlm.nih.gov/pubmed/34368471 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2021.101086 |
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