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SPIN4 is a principal endogenous substrate of the E3 ubiquitin ligase DCAF16
DCAF16 is a substrate recognition component of Cullin-RING E3 ubiquitin ligases that can be targeted by electrophilic PROTACs (PROteolysis Targeting Chimeras) to promote the nuclear-restricted degradation of proteins. The endogenous protein substates of DCAF16 remain unknown. In this study, we compa...
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| Udgivet i: | Biochemistry |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8325951/ https://ncbi.nlm.nih.gov/pubmed/33636084 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.1c00067 |
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