Copper Sulfide Facilitates Hepatobiliary Clearance of Gold Nanoparticles through the Copper-Transporting ATPase ATP7B

Metallic gold (Au) nanoparticles have great potential for a wide variety of biomedical applications. Yet, slow clearance of Au nanoparticles significantly hinders their clinical translation. Herein, we describe a strategy of utilizing the endogenous copper (Cu) clearance to improve the elimination o...

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Pubblicato in:ACS Nano
Autori principali: Wang, Xiaodong, Guo, Liangran, Zhang, Sihang, Chen, Yuan, Chen, Yi-Tzai, Zheng, Binbin, Sun, Jingwen, Qian, Yuyi, Chen, Yixin, Yan, Bingfang, Lu, Wei
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8325778/
https://ncbi.nlm.nih.gov/pubmed/30973228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsnano.9b01154
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