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Structural basis for GTP versus ATP selectivity in the NMP kinase AK3

ATP and GTP are exceptionally important molecules in biology with multiple, and often discrete, functions. Therefore, enzymes that bind to either of them must develop robust mechanisms to selectively utilize one or the other. Here, this specific problem is addressed by molecular studies of the human...

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Detalles Bibliográficos
Publicado en:Biochemistry
Main Authors: Rogne, Per, Dulko-Smith, Beata, Goodman, Jack, Rosselin, Marie, Grundström, Christin, Hedberg, Christian, Nam, Kwangho, Sauer-Eriksson, A. Elisabeth, Wolf-Watz, Magnus
Formato: Artigo
Idioma:Inglês
Publicado: 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8325564/
https://ncbi.nlm.nih.gov/pubmed/32822537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.0c00549
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