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Structural basis for GTP versus ATP selectivity in the NMP kinase AK3

ATP and GTP are exceptionally important molecules in biology with multiple, and often discrete, functions. Therefore, enzymes that bind to either of them must develop robust mechanisms to selectively utilize one or the other. Here, this specific problem is addressed by molecular studies of the human...

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Dettagli Bibliografici
Pubblicato in:Biochemistry
Autori principali: Rogne, Per, Dulko-Smith, Beata, Goodman, Jack, Rosselin, Marie, Grundström, Christin, Hedberg, Christian, Nam, Kwangho, Sauer-Eriksson, A. Elisabeth, Wolf-Watz, Magnus
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8325564/
https://ncbi.nlm.nih.gov/pubmed/32822537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.0c00549
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