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Biomaterial-facilitated Immunotherapy for Established Oral Cancers

We evaluated a peptide-based immunotherapy termed SynerGel: an injectable, biomaterial-based platform for intratumoral drug delivery. A drug-mimicking peptide hydrogel named L-NIL-MDP was loaded with an anti-tumor cyclic dinucleotide (CDN) immunotherapy agonist. The biomaterial combines inducible Ni...

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Detalhes bibliográficos
Publicado no:ACS Biomater Sci Eng
Main Authors: Leach, David G., Dharmaraj, Neeraja, Lopez-Silva, Tania L., Venzor, Jose Rodriguez, Pogostin, Brett H., Sikora, Andrew G., Hartgerink, Jeffrey D., Young, Simon
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8325389/
https://ncbi.nlm.nih.gov/pubmed/33470801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsbiomaterials.0c01575
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