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Biomaterials for vaccine-based cancer immunotherapy
The idea of developing therapeutic vaccines against cancer has been explored since the early discovery of tumor-specific antigens by Georg Klein in 1967. However, challenges including weak immunogenicity, systematic toxicity, and off-target effects of cancer vaccines remain as barriers to their broa...
Gardado en:
| Publicado en: | J Control Release |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6355332/ https://ncbi.nlm.nih.gov/pubmed/30312721 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2018.10.008 |
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