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Biomaterials for vaccine-based cancer immunotherapy

The idea of developing therapeutic vaccines against cancer has been explored since the early discovery of tumor-specific antigens by Georg Klein in 1967. However, challenges including weak immunogenicity, systematic toxicity, and off-target effects of cancer vaccines remain as barriers to their broa...

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Bibliografiske detaljer
Udgivet i:J Control Release
Main Authors: Zhang, Rui, Billingsley, Margaret M., Mitchell, Michael J.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6355332/
https://ncbi.nlm.nih.gov/pubmed/30312721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2018.10.008
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