Inside-out regulation of E-cadherin conformation and adhesion

Cadherin cell–cell adhesion proteins play key roles in tissue morphogenesis and wound healing. Cadherin ectodomains bind in two conformations, X-dimers and strand-swap dimers, with different adhesive properties. However, the mechanisms by which cells regulate ectodomain conformation are unknown. Cad...

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Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Koirala, Ramesh, Priest, Andrew Vae, Yen, Chi-Fu, Cheah, Joleen S., Pannekoek, Willem-Jan, Gloerich, Martijn, Yamada, Soichiro, Sivasankar, Sanjeevi
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2021
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8325368/
https://ncbi.nlm.nih.gov/pubmed/34301871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2104090118
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