Evolution of a σ–(c-di-GMP)–anti-σ switch

Filamentous actinobacteria of the genus Streptomyces have a complex lifecycle involving the differentiation of reproductive aerial hyphae into spores. We recently showed c-di-GMP controls this transition by arming a unique anti-σ, RsiG, to bind the sporulation-specific σ, WhiG. The Streptomyces vene...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Schumacher, Maria A., Gallagher, Kelley A., Holmes, Neil A., Chandra, Govind, Henderson, Max, Kysela, David T., Brennan, Richard G., Buttner, Mark J.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2021
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8325347/
https://ncbi.nlm.nih.gov/pubmed/34290147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2105447118
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