Differential effects of the cell cycle inhibitor, olomoucine, on functional recovery and on responses of peri-infarct microglia and astrocytes following photothrombotic stroke in rats

BACKGROUND: Following stroke, changes in neuronal connectivity in tissue surrounding the infarct play an important role in both spontaneous recovery of neurological function and in treatment-induced improvements in function. Microglia and astrocytes influence this process through direct interactions...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Yew, Wai Ping, Djukic, Natalia D., Jayaseelan, Jaya S. P., Woodman, Richard J., Muyderman, Hakan, Sims, Neil R.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8325288/
https://ncbi.nlm.nih.gov/pubmed/34332596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-021-02208-w
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