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Molecular features and vulnerabilities of recurrent chordomas

BACKGROUND: Tumor recurrence is one of the major challenges in clinical management of chordoma. Despite R0-resection, approximately 50% of chordomas recur within ten years after initial surgery. The underlying molecular processes are poorly understood resulting in the lack of associated therapeutic...

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Publicat a:J Exp Clin Cancer Res
Autors principals: Seeling, Carolin, Lechel, André, Svinarenko, Michael, Möller, Peter, Barth, Thomas F. E., Mellert, Kevin
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2021
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8325178/
https://ncbi.nlm.nih.gov/pubmed/34330313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-021-02037-y
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