MicroRNA-186 ameliorates Knee osteoarthritis via regulation of P2X7-mediated Cathepsin-K/Runx2/ADAMTS5 signalling axis in articular chondrocytes

Knee osteoarthritis (KOA) is a chronic joint disorder involving the articular cartilage and tissues around the synovial joint. The key objective of this study was to determine the effect of miR-186-5p administration on the expression of pathogenic signalling in the chondrocytes using a surgical dest...

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Detalhes bibliográficos
Publicado no:Saudi J Biol Sci
Main Authors: Deng, RuLin, Zhang, HongJun, Huang, Lei, Xiong, Xin, Fu, Xiaoling
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8324999/
https://ncbi.nlm.nih.gov/pubmed/34354409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sjbs.2021.06.091
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