Activation of transient receptor potential vanilloid 4 protects articular cartilage against inflammatory responses via CaMKK/AMPK/NF-κB signaling pathway

Transient receptor potential vanilloid 4 (TRPV4) plays an important role in chondrocytes via Ca(2+) signaling. However, its role in the progression of osteoarthritis is unclear. This study aimed to evaluate the effects of TRPV4 activation on articular cartilage and chondrocytes stimulated with inter...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Hattori, Kyosuke, Takahashi, Nobunori, Terabe, Kenya, Ohashi, Yoshifumi, Kishimoto, Kenji, Yokota, Yutaka, Suzuki, Mochihito, Kojima, Toshihisa, Imagama, Shiro
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8324869/
https://ncbi.nlm.nih.gov/pubmed/34330980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-94938-3
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