Beige adipocytes mediate the neuroprotective and anti-inflammatory effects of subcutaneous fat in obese mice

Visceral obesity increases risk of cognitive decline in humans, but subcutaneous adiposity does not. Here, we report that beige adipocytes are indispensable for the neuroprotective and anti-inflammatory effects of subcutaneous fat. Mice lacking functional beige fat exhibit accelerated cognitive dysf...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Guo, De-Huang, Yamamoto, Masaki, Hernandez, Caterina M., Khodadadi, Hesam, Baban, Babak, Stranahan, Alexis M.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2021
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8324783/
https://ncbi.nlm.nih.gov/pubmed/34330904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-24540-8
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