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Tailoring the effect of antithrombin-targeting therapy in haemophilia A using in silico thrombin generation
Factor (F) VIII deficiency causes bleeding in haemophilia A patients because of the reduced formation of procoagulant enzyme thrombin, which is needed to make the blood clot. We measured the dynamics of coagulation in haemophilia A patients by measuring thrombin generation (TG). Additionally, we qua...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8324778/ https://ncbi.nlm.nih.gov/pubmed/34330995 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-95066-8 |
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