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Uncoupling of gene expression from copy number presents therapeutic opportunities in aneuploid cancers
Uncoupling of mRNA expression from copy number (UECN) might be a strategy for cancer cells to a tolerate high degree of aneuploidy. To test the extent and role of UECN across cancers, we perform integrative multiomic analysis of The Cancer Genome Atlas (TCGA) dataset, encompassing ∼5,000 individual...
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| 出版年: | Cell Rep Med |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Elsevier
2021
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8324495/ https://ncbi.nlm.nih.gov/pubmed/34337565 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xcrm.2021.100349 |
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