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In vivo reprogramming of pathogenic lung TNFR2(+) cDC2s by IFNβ inhibits HDM-induced asthma
Asthma is a common inflammatory lung disease with no known cure. Previously, we uncovered a lung TNFR2(+) conventional DC2 subset (cDC2s) that induces regulatory T cells (T(regs)) maintaining lung tolerance at steady state but promotes T(H)2 response during house dust mite (HDM)–induced asthma. Lung...
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| Publicado no: | Sci Immunol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8323989/ https://ncbi.nlm.nih.gov/pubmed/34244314 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.abi8472 |
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