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MicroRNA-10a negatively regulates CD4(+) T cell IL-10 production through suppression of Blimp1

An uncontrolled CD4(+) T cell response is a critical hallmark of autoimmune diseases. IL-10, which can be produced by both effector and regulatory CD4(+) T cells, plays an essential role in the inhibition of autoimmunity. MicroRNAs (miRNAs) are key molecules involved in regulating immune responses....

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Yang, Wenjing, Chen, Liang, Xu, Leiqi, Bilotta, Anthony J., Yao, Suxia, Liu, Zhanju, Cong, Yingzi
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8323958/
https://ncbi.nlm.nih.gov/pubmed/34301843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.2100017
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