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RNA modification of an RNA modifier prevents self-RNA sensing
A new study in PLOS Biology finds that interferon (IFN)-induced adenosine deaminase acting on RNA 1 (ADAR1) mRNA is N6-methyladenosine (m(6)A) modified to promote its translation, enabling ADAR1 to modify self-double-stranded RNAs (dsRNAs) generated during the IFN response and preventing activation...
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| Publicado en: | PLoS Biol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science
2021
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8323910/ https://ncbi.nlm.nih.gov/pubmed/34329302 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3001342 |
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