The mRNA Cap 2′-O-Methyltransferase CMTR1 Regulates the Expression of Certain Interferon-Stimulated Genes

Type I interferons (IFN) initiate an antiviral state through a signal transduction cascade that leads to the induction of hundreds of IFN-stimulated genes (ISGs) to restrict viral infection. Recently, RNA modifications on both host and viral RNAs have been described as regulators of infection. Howev...

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Bibliographic Details
Published in:mSphere
Main Authors: Williams, Graham D., Gokhale, Nandan S., Snider, Daltry L., Horner, Stacy M.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2020
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7227766/
https://ncbi.nlm.nih.gov/pubmed/32404510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSphere.00202-20
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