Brevibacillin 2V Exerts Its Bactericidal Activity via Binding to Lipid II and Permeabilizing Cellular Membranes

Lipo-tridecapeptides, a class of bacterial non-ribosomally produced peptides, show strong antimicrobial activity against Gram-positive pathogens, including antibiotic-resistant Staphylococcus aureus and Enterococcus spp. However, many of these lipo-tridecapeptides have shown high hemolytic activity...

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Bibliografiske detaljer
Udgivet i:Front Microbiol
Main Authors: Zhao, Xinghong, Wang, Xiaoqi, Shukla, Rhythm, Kumar, Raj, Weingarth, Markus, Breukink, Eefjan, Kuipers, Oscar P.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Microbiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8322648/
https://ncbi.nlm.nih.gov/pubmed/34335524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2021.694847
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