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ADAM12 is a costimulatory molecule that determines Th1 cell fate and mediates tissue inflammation

A disintegrin and metalloproteinase (ADAM)12 was previously found to be expressed in T cells in the inflamed brain. However, the function of ADAM12 in T-cell responses in general and in tissue inflammation has not been examined. Here, we studied the role of ADAM12 in T-cell responses, fate determina...

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Publicat a:Cell Mol Immunol
Autors principals: Liu, Yawei, Bockermann, Robert, Hadi, Mahdieh, Safari, Iman, Carrion, Belinda, Kveiborg, Marie, Issazadeh-Navikas, Shohreh
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8322154/
https://ncbi.nlm.nih.gov/pubmed/32572163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41423-020-0486-8
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