Local therapy with CpG motifs in a murine model of allergic airway inflammation in IFN-β knock-out mice

BACKGROUND: CpG oligodeoxynucleotides (CpG-ODN) are capable of inducing high amounts of type I IFNs with many immunomodulatory properties. Furthermore, type-I IFNs have been proposed to play a key role in mediating effects of CpG-ODN. The precise role of IFN-β in the immunomodulatory effects of CpG-...

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Main Authors: Matheu, Victor, Treschow, Alexandra, Teige, Ingrid, Navikas, Vaidrius, Issazadeh-Navikas, Shohreh
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2005
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC555575/
https://ncbi.nlm.nih.gov/pubmed/15748290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-6-25
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