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Two transition states of the glycogen shunt and two steady states of gene expression support metabolic flexibility and the Warburg effect in cancer

Previously we suggested that the early Warburg effect can be explained by the use by cancer cells the glycogen shunt during a rapid increase in glucose concentration. In analogy to the Crabtree effect in yeast, the shunt plays a critical role in maintaining homeostasis of glycolytic intermediate lev...

詳細記述

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書誌詳細
出版年:Neoplasia
主要な著者: Rothman, Douglas L, Shulman, Robert G.
フォーマット: Artigo
言語:Inglês
出版事項: Neoplasia Press 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8322124/
https://ncbi.nlm.nih.gov/pubmed/34303218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2021.06.004
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