Torpor enhances synaptic strength and restores memory performance in a mouse model of Alzheimer’s disease

Hibernation induces neurodegeneration-like changes in the brain, which are completely reversed upon arousal. Hibernation-induced plasticity may therefore be of great relevance for the treatment of neurodegenerative diseases, but remains largely unexplored. Here we show that a single torpor and arous...

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Pubblicato in:Sci Rep
Autori principali: de Veij Mestdagh, Christina F., Timmerman, Jaap A., Koopmans, Frank, Paliukhovich, Iryna, Miedema, Suzanne S. M., Goris, Maaike, van der Loo, Rolinka J., Krenning, Guido, Li, Ka Wan, Mansvelder, Huibert D., Smit, August B., Henning, Robert H., van Kesteren, Ronald E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8322095/
https://ncbi.nlm.nih.gov/pubmed/34326412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-94992-x
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